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PubMed · 10609871

Utilization of vitamin E.

M G Traber
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Abstract

Natural (RRR) or synthetic (all-rac) forms of alpha-tocopherol are available (usually as acetate esters) for use as vitamin E supplements. In animal tests, the natural stereoisomer, RRR-alpha-tocopheryl acetate, is 1.36 times more biologically potent than all-rac-alpha-tocopheryl acetate, an equimolar mixture of eight stereoisomers [8,15,40-43]. The higher biologic activity of natural compared with synthetic vitamin E does not result from differences in antioxidant activity [2,3], but could hypothetically be explained by differences in (1) absorption, (2) plasma transport, (3) delivery to tissues, or (4) metabolism. These possibilities will be considered in this review.

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AnimalsHumansIntestinal AbsorptionTissue DistributionVitamin EJournal ArticleReview

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M G Traber. 1999. Utilization of vitamin E.. https://doi.org/10.1002/biof.5520100205

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