Lessons from gene modified mice.

S Lira

PubMed · 10611406

Lessons from gene modified mice.

Abstract

Chemokines have been implicated in leukocyte trafficking, angiogenesis, immunoregulation and development. Understanding these and other chemokine functions in vivo is an enormously complex task, but one that is being facilitated by the application of powerful genetic techniques. Here I will summarise the results of a variety of genetic studies in mice and discuss how they have helped us to understand the biological role of chemokines and their receptors.

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Animals Chemokines Disease Models, Animal Genetic Engineering Genetic Techniques Immunocompetence Leukocytes Mice Mice, Knockout Mice, Transgenic Neovascularization, Pathologic Journal Article Review

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S Lira. Lessons from gene modified mice.. https://pubmed.ncbi.nlm.nih.gov/10611406/

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