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PubMed · 10617846

[Sarcoid optic neuropathy].

C Brindeau·A Glacet-Bernard·B Roualdes·I Abd Alsamad·H Oubraham·C Meyrignac·G Soubrane
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Abstract

Sarcoidosis is a multisystem granulomatous disease mostly involving the chest. Sarcoid optic neuropathy is an uncommon but serious manifestation that requires long-term corticosteroid treatment. We report here the case of a 50-year-old black patient complaining of a recent blurred vision on his left eye. The ophthalmologic examination was normal. Goldmann visual field and visual evoked potentials confirmed the diagnosis of retrobulbar optic neuropathy. Sarcoidosis was presumed on a chest radiography and computed tomography and confirmed with a transbronchial biopsy. Symptoms disappeared with intravenous bolus of corticosteroids. Three months later, without treatment, a right inferior eyelid tumor was observed. Magnetic resonance imaging (RMI) showed two orbital masses and multiple meningeal lesions enhancing with contrast suggesting neurosarcoidosis which decreased with a long-term high-dose corticosteroid therapy (1 mg/kg/d). Optic neuropathy is a rare manifestation of neurosarcoidosis, mostly accompanied by optic-disc involvement with papillary lesions. Chest roentgenogram and computed tomography give a presumption of sarcoidosis. But biopsy is mandatory to confirm the diagnosis demonstrating the histologic lesion of a non caseating granulomatous. Corticosteroid therapy is dramatically efficient but sometimes several months treatment is required.

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Black PeopleEvoked Potentials, VisualFemaleFranceHumansMagnetic Resonance ImagingMiddle AgedOptic NerveOptic Nerve DiseasesSarcoidosisVisual FieldsCase ReportsJournal Article

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C Brindeau, A Glacet-Bernard, B Roualdes, I Abd Alsamad, H Oubraham, C Meyrignac, G Soubrane. 1999. [Sarcoid optic neuropathy].. https://pubmed.ncbi.nlm.nih.gov/10617846/

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