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Apoptotic and effector pathways in autoimmunity.

A V Chervonsky
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Abstract

Programmed cell death is an important anti-autoimmune mechanism used to delete autoreactive lymphocytes and to limit the spread both of viral infections and of tissue damage caused by immune responses. However, in autoimmune diseases, activation of programmed cell death by effector mechanisms that are similar to the normal immune response leads to augmented destruction of the targeted tissues.

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AnimalsApoptosisAutoimmune DiseasesHumansJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Review

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A V Chervonsky. 1999. Apoptotic and effector pathways in autoimmunity.. https://doi.org/10.1016/s0952-7915(99)00037-0

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