Viral-encoded cyclins.

H Laman; D J Mann; N C Jones

doi:10.1016/s0959-437x(99)00045-3

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PubMed · 10679390

Viral-encoded cyclins.

H Laman·D J Mann·N C Jones

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Abstract

D-type cyclin homologs have been found in the genomes of herpesviruses associated with neoplasias. They appear to exploit features of G(1) cyclins but extend their properties to allow for deregulation of the cell cycle. Advances in the study of the molecular basis for these novel features as well as the potential role of viral cyclins in tumorigenesis are addressed.

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Animals Cell Cycle Cyclin-Dependent Kinase Inhibitor p21 Cyclin-Dependent Kinases Cyclins Herpesviridae Humans Neoplasms Oncogenes Viral Proteins Journal Article Review

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H Laman, D J Mann, N C Jones. 2000. Viral-encoded cyclins.. https://doi.org/10.1016/s0959-437x(99)00045-3

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