Accessory molecules for MHC class II peptide loading.

R Busch; R C Doebele; N S Patil; A Pashine; E D Mellins

doi:10.1016/s0952-7915(99)00057-6

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Accessory molecules for MHC class II peptide loading.

R Busch·R C Doebele·N S Patil·A Pashine·E D Mellins

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Abstract

Accessory molecules, such as HLA-DM and invariant chain, modulate the ligands bound to MHC class II molecules in antigen-presenting cells. Recent investigations, including gene targeting experiments, have shed light on the functions of these molecules, their mechanisms of action, interactions with class II molecules, and the relationships with associated molecules such as tetraspanins and HLA-DO.

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Animals Antigen Presentation Antigens, Differentiation, B-Lymphocyte Dendritic Cells HLA-D Antigens HLA-DR3 Antigen Histocompatibility Antigens Class II Humans Membrane Proteins Mice Protein Binding Journal Article Review

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R Busch, R C Doebele, N S Patil, A Pashine, E D Mellins. 2000. Accessory molecules for MHC class II peptide loading.. https://doi.org/10.1016/s0952-7915(99)00057-6

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