Inflammatory bowel disease: immunologic concepts.

S Schreiber

PubMed · 10690582

Inflammatory bowel disease: immunologic concepts.

Abstract

The past decade has been characterized by an enormous progress in the understanding of the pathophysiology of chronic intestinal inflammation. Novel drugs, which include tumor necrosis factor alpha binding proteins (i.e., the monoclonal antibody infliximab), have been introduced into the therapeutic management of Crohn's disease. With our increasing knowledge of disease pathophysiology and the identification of key mediators, it is to be expected that the efficacy of anti-inflammatory therapy will further increase. The exploration of the genetic etiology of inflammatory bowel disease holds great future promises.

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Antigen Presentation Cytokines Humans Inflammatory Bowel Diseases Lymphocyte Activation Signal Transduction T-Lymphocytes Journal Article Research Support, Non-U.S. Gov't Review

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S Schreiber. Inflammatory bowel disease: immunologic concepts.. https://pubmed.ncbi.nlm.nih.gov/10690582/

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