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PubMed · 10691595

Mycophenolate mofetil-induced dyshidrotic eczema.

S Semhoun-Ducloux·D Ducloux·J P Miguet
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Eczema, DyshidroticFemaleFoot DermatosesHand DermatosesHumansImmunosuppressive AgentsMiddle AgedMycophenolic AcidCase ReportsLetter

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S Semhoun-Ducloux, D Ducloux, J P Miguet. 2000-03-07. Mycophenolate mofetil-induced dyshidrotic eczema.. https://doi.org/10.7326/0003-4819-132-5-200003070-00015

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Dyshidrosis is a common chronic dermatitis of the hands and feet that may cause significant physical discomfort, psychological distress, and occupational impairment. Topics reviewed in this article include epidemiology, clinical findings, quality of life, and therapeutic considerations. Dyshidrosis is often difficult to manage; therefore, extra attention is given in this review article to current treatment options.

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PubMed1999

The Dyshidrotic Eczema Area and Severity Index - A score developed for the assessment of dyshidrotic eczema.

BACKGROUND: Dyshidrotic eczema of the palms and soles is a common condition, which can be rather resistant to treatment. Therapy studies and their comparability are of clinical importance. OBJECTIVE: As standardized assessment methods for the severity of this particular form of eczema are lacking, we developed a severity index for dyshidrotic eczema. METHODS: The Dyshidrotic Eczema Area and Severity Index (DASI) is based on the severity grade of single items - number of vesicles per square centimetre (V), erythema (E), desquamation (S) and itch (I) - and the extension of the affected area (A) and is calculated with defined score points (p) as: DASI = (pv + pE = pS + pI) x pA. RESULTS: In two treatment studies on dyshidrotic hand eczema, the DASI was found to be a simple and useful tool to assess the severity of dyshidrotic eczema and the effect of therapy. CONCLUSION: The DASI needs to be further validated in larger cohorts.

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