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PubMed · 10714185

Autoimmune hepatitis--a diagnostic challenge.

A Ahmad·E Thomas
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Abstract

Autoimmune hepatitis is a type of chronic hepatitis characterized by hypergammaglobulinemia, hypertransaminasemia, presence of autoantibodies, and active necroinflammatory process in the liver revealed by histology. Its onset is usually acute and has a bad prognosis. Tissue antibodies are found in large proportions of patients. Women outnumber men in a 2-3:1 ratio, and it is mostly young women who are affected. Ten percent of all affected have severe disease characterized by elevations of serum aminotransferase levels greater than five-fold, along with a two-fold elevation of gamma globulin or a 10-fold elevation of serum aminotransferase levels alone. We present an unusual case of this disorder in a 60-year-old male patient manifesting its severe form.

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Diagnosis, DifferentialFemaleHepatitis, AutoimmuneHumansLiver Function TestsMaleMiddle AgedCase ReportsJournal Article

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A Ahmad, E Thomas. 2000. Autoimmune hepatitis--a diagnostic challenge.. https://pubmed.ncbi.nlm.nih.gov/10714185/

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