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Two-component and phosphorelay signal transduction.

J A Hoch
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Abstract

Two-component and phosphorelay signal transduction systems are the major means by which bacteria recognize and respond to a variety of environmental stimuli. Recent results have implicated these systems in the regulation of a variety of essential processes including cell-cycle progression, pathogenicity, and developmental pathways. Elucidation of the structures of the interacting domains is leading to an understanding of the mechanisms of molecular recognition and phosphotransfer in these systems.

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BacteriaBacterial ProteinsGenes, RegulatorPhosphorylationProtein KinasesProtein Structure, TertiarySignal TransductionTranscription FactorsJournal ArticleResearch Support, U.S. Gov't, P.H.S.Review

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J A Hoch. 2000. Two-component and phosphorelay signal transduction.. https://doi.org/10.1016/s1369-5274(00)00070-9

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