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Designer egg evaluation in a controlled trial.

P F Surai·A MacPherson·B K Speake·N H Sparks
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Abstract

OBJECTIVE: To evaluate the ability of designer eggs enriched in vitamin E, lutein, selenium (Se) and docosahexaenoic acid (DHA) to deliver micronutrients to the human in a palatable and visually acceptable form. DESIGN: Double-blind, placebo-controlled trial, two treatment groups balanced for sex and age. SETTING: Department of Biochemistry and Nutrition, SAC, Scotland. SUBJECTS: Forty healthy adult volunteers completed the study. Volunteers were recruited among staff of the Scottish Agricultural College Interventions: Volunteers consumed, for 8 weeks, either a designer egg or a normal table egg per day. Fasting blood samples were taken before and at the end of the study. RESULTS: Consumption of designer eggs enriched in vitamin E, lutein, Se and DHA significantly increased the levels of alpha-tocopherol, lutein and DHA in plasma as compared to the changes found after consumption of normal table eggs, with the largest increases found in plasma lutein (1.88-fold increase). The proportion of DHA was increased in all the main lipid classes of the plasma including triacylglycerol (2.3-fold), free fatty acids (1. 6-fold), cholesteryl ester (1.4-fold) and phospholipid (1.3-fold). Egg consumption did not change Se concentration in plasma, blood pressure, total plasma lipid concentrations or the concentrations of total cholesterol and HDL-cholesterol in plasma. CONCLUSION: Consumption of designer eggs enriched in vitamin E, lutein, DHA and Se as part of normal diet for 8 weeks effectively increased the blood levels of alpha-tocopherol, lutein and DHA. SPONSORSHIP: Scottish Office Agriculture, Environment, and Fisheries Department.

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AdultBlood PressureCholesterol, HDLChromatography, High Pressure LiquidDocosahexaenoic AcidsDouble-Blind MethodEggsFemaleHumansLuteinMaleMicronutrientsMiddle AgedSeleniumVitamin EClinical TrialJournal ArticleRandomized Controlled TrialResearch Support, Non-U.S. Gov't

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P F Surai, A MacPherson, B K Speake, N H Sparks. 2000. Designer egg evaluation in a controlled trial.. https://doi.org/10.1038/sj.ejcn.1600939

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