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PubMed · 10752336

[Optic disc blood flow measured by scanning laser-Doppler flowmetry using a new analysis program].

N Hayashi·G Tomita·Y Kitazawa
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Abstract

PURPOSE: Using a new analysis program for scanning laser-Doppler flowmetry (SLDF) by a Heidelberg retina flowmeter (HRF), we studied the relation between flow and visual field or disc morphology. SUBJECTS AND METHODS: In 42 eyes of 21 patients with normal tension glaucoma (NTG) the mean-flow of the HRF blood flow parameters at the disc rim was measured and analyzed by a new analysis program for perfusion maps (the SLDF analysis tool), to minimize the influence of large vessels or/and artifacts caused by small eye movements. We investigated whether difference of the mean-flow between a pair of eyes had any relation to differences between a pair of eyes in visual field indices and those in disc morphological measurements of the Heidelberg retina tomograph. RESULTS: We found statistically significant correlations between the mean-flow and optic disc parameters (Disk Area, Cup Area, Height Variation Contour, Cup Volume, Rim Volume, Mean RNFL Thickness). We found no statistically significant correlations between the mean-flow and visual field parameters (mean deviation, corrected pattern standard deviation). CONCLUSION: The results suggested that eyes with less flow in the optic disc rim have more advanced glaucomatous morphological changes.

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AdultAgedFemaleHumansLaser-Doppler FlowmetryMaleMiddle AgedOptic DiskVisual FieldsEnglish AbstractJournal Article

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N Hayashi, G Tomita, Y Kitazawa. 2000. [Optic disc blood flow measured by scanning laser-Doppler flowmetry using a new analysis program].. https://pubmed.ncbi.nlm.nih.gov/10752336/

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