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Manganese intoxication.

J W Lee
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Abstract

Manganese plays an important role as a cofactor in many enzymatic reactions in humans but in excess amounts can cause irreversible nervous system damage. Although manganism is a rare condition, it can be the cause of complex nervous system symptoms, especially in the setting of environmental exposure. Specifically, manganese is a well-known cause of dystonic parkinsonism. This article highlights several historical descriptions of the clinical manifestations, pathological changes, and attempted therapeutic intervention in manganese intoxication.

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AnimalsHistory, 19th CenturyHistory, 20th CenturyHumansMaleManganese PoisoningOccupational ExposureParkinson Disease, SecondaryHistorical ArticleJournal Article

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BibTeXRIS

J W Lee. 2000. Manganese intoxication.. https://doi.org/10.1001/archneur.57.4.597

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