PubMed Health⌕ Search

PubMed · 10773907

Augmenting cognitive learning of community nutrition by tutorials.

Abstract

Community health interventions are increasingly being considered a priority area in medical curriculum. In the topic of nutrition, a situation analysis of final MBBS students in our institution revealed significantly lower levels of knowledge in community applications as compared to basics and clinical aspects, indicating the need for some educational intervention. An improvised tutorial was conducted to address this deficiency at cognitive level. The intervention was a special scheme of flow of discussion with a positive bias in favour of nutritional applications at community level. Half of the learners were given routine tutorial, as part of existing teaching schedule in nutrition and the remaining were subjected to educational intervention, to provide control and study groups respectively. Before and after assessment of the recall of learners on community applications demonstrated a positive impact of improvised tutorial. The learners' level of knowledge in two groups was comparable before the tutorial but it was significantly higher ('P' < 0.001) in study group as compared to control, after the tutorial (mean scores: 134.38/150 and 91.20/150 respectively). No extra resources, tutor time or student's learning hours were needed for the improvised tutorial. Tutor's positive bias in favour of applied aspects can bring about a desired change even in conventional teaching-learning process, without asking for extra resources. It can be a supplement to community-based learning.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

S Chaturvedi. Augmenting cognitive learning of community nutrition by tutorials.. https://doi.org/10.1007/bf02730898

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Prevalence and risk factors for persistent faecal carriage of extended spectrum beta-lactamase producing Escherichia coli in a paediatric community population.

OBJECTIVE: To investigate clinical and microbiological factors associated with persistent faecal carriage of extended spectrum beta-lactamase (ESBL) producing Escherichia coli in infants. METHODS: Between 2010 and 2022, children aged 3 months to 2 years old were sampled in a community setting in France, at two visits, V1 and V2, 3-24&#x202f;months apart, to screen for prolonged faecal carriage of ESBL-producing E. coli. Patient clinical information and whole genome sequence of each isolate were used for association studies. RESULTS: A total of 4641 children were sampled. 375 (8%) carried an ESBL-producing Enterobacterales, among which 142 of ESBL-producing E. coli carriers were once again sampled at V2 and included in this study. 21.8% (n&#x202f;=&#x202f;31/142) and 18.4% (n&#x202f;=&#x202f;16/99) carried the same ESBL-producing E. coli clone for at least 3 and 6 months, respectively. B2 phylogroup, and among which ST131 clones were associated with an increased risk of persistent carriage. Multivariate analysis identified virulence associated genes involved in adhesion (papC/papGII allele and a tia-like gene) and encoding toxin (senB) as major risk factors for persistence. A genome wide association study highlighted the potential role of the frz metabolic operon, known to be involved in enterocytes adhesion/internalisation. CONCLUSION: Main extraintestinal pathogenic E. coli genomic features (phylogenetic background, adhesion properties) are associated with ESBL-producing E. coli gut colonisation persistence in infants, which could potentially lead to an increased risk of febrile urinary tract infection in these patients.

Child↗

Extensive and differential platinum chemotherapy mutagenesis in livers of children.

Childhood cancer survivors often experience late adverse effects that may be linked to chemotherapy mutagenesis. We studied chemotherapy mutagenesis in normal pediatric tissues using duplex sequencing (NanoSeq) to enable the detection of mutations from single DNA molecules. We found that platinum chemotherapeutics increased the mutation burdens of normal pediatric tissues to levels seen in adults. In the liver, platinum agents imparted a tissue-specific mutational signature that was absent from other tissues. Gene-focused duplex sequencing revealed that chemotherapy mutagenesis generates a great diversity of nonsynonymous variants, some of which may have functional potential, such as leukemogenic variants in blood. Our findings demonstrate extensive chemotherapy mutagenesis in normal tissues of children, which may provide a plausible link between chemotherapy exposure and adverse effects in later life.

Child↗

Clinical and immunological characterization of a child with a homozygous TBK1 kinase-domain truncation.

TBK1 is a serine-tyrosine kinase protein that transmits signals from pattern recognition receptors to the NF-&#x3ba;B pathway leading to production of Type 1 Interferons. Mutations in this protein have been associated with arthritis, vasculitis, herpes simplex encephalitis and amyotrophic lateral sclerosis. In the current study, we characterized the functional consequences of a TBK1-variant bearing a truncation in exon 4 and 5 in a patient with poly arthritis resembling juvenile idiopathic arthritis and necrotizing encephalitis. The truncation was associated with reduced TBK1 protein abundance and altered phosphorylation. The variant was associated with increased basal/and or Poly-I: C induced IL-6, TNF&#x3b1;, IL-1&#x3b2; and IL-18 and type 1 Interferon ex vivo. Our findings expand the phenotypic spectrum of TBK1 loss-of-function variants and may provide insight into the management of immune dysregulation in affected patients.

Child↗