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PubMed · 10789149

[Experimental models in epilepsy].

D Contreras
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Abstract

INTRODUCTION: Epilepsy is an heterogeneous collection of neurological disorders that have in common a transient and recurrent hypersynchronous activation of large populations of neurons in distinct focal areas or in the entire brain. DEVELOPMENT: Research into the cellular mechanisms of epilepsy focuses on understanding. 1. The alterations on cellular and network excitability, and 2. The mechanisms of hypersynchronization. Several different animal models exist that mimic different types of focal and generalized epilepsy in humans. Hypothesis derived from such models is helping to design more effective therapies.

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AnticonvulsantsCerebral CortexElectroencephalographyEpilepsyHumansNeuronsReceptors, GABASleepEnglish AbstractJournal ArticleReview

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D Contreras. [Experimental models in epilepsy].. https://pubmed.ncbi.nlm.nih.gov/10789149/

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