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PubMed · 10797600

Caenorhabditis elegans.

J Wixon·M Blaxter·I Hope·R Barstead·S Kim
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Abstract

Transparent, free-living nematode worm. Unsegmented body plan with full set of differentiated tissues (neural, endoderm, ectoderm and muscle). Genome size approximately 97 Mb, as five autosomes and one X sex chromosome. Fully sequenced genome, which comprises approximately 20 000 predicted genes. Defined cell lineage. Has made major contribution to studies of development, cell-to-cell signalling, cell ageing and cell death processes. Large-scale gene deletion, microarray analysis of gene expression and two-hybrid protein interaction analysis projects under way. Comparative studies mainly with C. briggsae, but also with other free-living and parasitic nematodes.

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J Wixon, M Blaxter, I Hope, R Barstead, S Kim. 2000. Caenorhabditis elegans.. https://doi.org/10.1002/(sici)1097-0061(200004)17%3A1%3C37%3A%3Aaid-yea11%3E3.0.co%3B2-p

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