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PubMed · 10801429

Membrane cytoskeleton: PIP(2) pulls the strings.

T Nebl·S W Oh·E J Luna
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Abstract

A recent application of optical tweezers has shown that plasma membrane phosphatidylinositol 4,5-bisphosphate (PIP(2)) levels control adhesion of the membrane bilayer to the underlying cytoskeleton, by regulated direct binding of PIP(2) to cytoskeletal proteins and/or indirect effects on cytoskeleton structure.

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AnimalsCalciumCell MembraneCytoskeletonHumansIsoenzymesPhosphatidylinositol 4,5-DiphosphatePhospholipase C gammaPhosphoric Monoester HydrolasesType C PhospholipasesJournal ArticleResearch Support, U.S. Gov't, P.H.S.Review

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T Nebl, S W Oh, E J Luna. 2000-05-04. Membrane cytoskeleton: PIP(2) pulls the strings.. https://doi.org/10.1016/s0960-9822(00)00465-6

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