Nonsequence-specific DNA recognition: a structural perspective.

F V Murphy; M E Churchill

doi:10.1016/s0969-2126(00)00126-x

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Nonsequence-specific DNA recognition: a structural perspective.

F V Murphy·M E Churchill

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Abstract

Chromosomal proteins that form essential architectural components of chromatin bind and bend DNA with an intrinsic low degree of sequence preference. Comparisons made between two recently determined structures of high mobility group (HMG) protein-DNA complexes and other nonsequence-specific protein-DNA complexes reveal the structural basis of this important mode of DNA binding.

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Archaeal Proteins Binding Sites DNA DNA-Binding Proteins High Mobility Group Proteins Models, Molecular Nucleic Acid Conformation Nucleosomes Protein Conformation Water Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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F V Murphy, M E Churchill. 2000-04-15. Nonsequence-specific DNA recognition: a structural perspective.. https://doi.org/10.1016/s0969-2126(00)00126-x

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