[Serotonin receptor knockout mice].

S Ishiura

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PubMed · 10803209

[Serotonin receptor knockout mice].

S Ishiura

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Abstract

The neurotransmitter serotonin is known to play a key role in determining emotional state in higher animals, especially in humans. Pharmacological studies have highlighted a subset of serotonin receptor subtypes (1A, 2B and 2C) worthy of knockout analysis. Several groups investigated knockout phenotype and determined the physiological function of these receptors, although the phenotype of the mouse seems somewhat paradoxical. However, the results strongly suggest that serotonin receptors are mainly involved in emotion (i.e., anxiety, aggressive behavior, obesity and epilepsy).

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Animals Humans Mice Mice, Knockout Receptors, Serotonin English Abstract Journal Article Review

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S Ishiura. 1999. [Serotonin receptor knockout mice].. https://pubmed.ncbi.nlm.nih.gov/10803209/

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