Dapsone hypersensitivity syndrome with coexisting acute hepatitis E.

A Chogle; A Nagral; A Soni; S Agale; Z Jamadar

PubMed · 10812824

Dapsone hypersensitivity syndrome with coexisting acute hepatitis E.

A Chogle·A Nagral·A Soni·S Agale·Z Jamadar

Abstract

A 14-year-old girl presented with fever, generalized lymphadenopathy, skin rash and hepatitis after starting dapsone. All abnormalities reversed with institution of prednisolone therapy after discontinuation of dapsone. The hepatic involvement was of hepatocellular type; it was associated with IgM anti-HEV antibodies, suggesting coexisting acute hepatitis E. We believe a causal link between the hepatotrophic viruses and dapsone hypersensitivity syndrome could exist.

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Acute Disease Adolescent Anti-Inflammatory Agents Dapsone Drug Hypersensitivity Female Hepatitis E Humans Leprostatic Agents Leprosy Prednisolone Syndrome Case Reports Journal Article

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A Chogle, A Nagral, A Soni, S Agale, Z Jamadar. Dapsone hypersensitivity syndrome with coexisting acute hepatitis E.. https://pubmed.ncbi.nlm.nih.gov/10812824/

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