Synaptic plasticity and dynamic modulation of the postsynaptic membrane.

C Lüscher; R A Nicoll; R C Malenka; D Muller

doi:10.1038/75714

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Synaptic plasticity and dynamic modulation of the postsynaptic membrane.

C Lüscher·R A Nicoll·R C Malenka·D Muller

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Abstract

The biochemical composition of the postsynaptic membrane and the structure of dendritic spines may be rapidly modulated by synaptic activity. Here we review these findings, discuss their implications for long-term potentiation (LTP) and long-term depression (LTD) and propose a model of sequentially occurring expression mechanisms.

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Animals Cell Size Dendrites Long-Term Potentiation Models, Neurological Nerve Tissue Proteins Neural Inhibition Neuronal Plasticity Pseudopodia Receptors, AMPA Signal Transduction Synapses Synaptic Membranes Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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C Lüscher, R A Nicoll, R C Malenka, D Muller. 2000. Synaptic plasticity and dynamic modulation of the postsynaptic membrane.. https://doi.org/10.1038/75714

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