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Solid-phase extraction followed by high-performance liquid chromatography-ionspray interface-mass spectrometry for monitoring of herbicides in environmental water.

R Curini·A Gentili·S Marchese·A Marino·D Perret
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Abstract

In this work we developed a sensitive and specific multiresidue method, based on reversed-phase liquid chromatography-mass spectrometry, with an ionspray interface (LC-ISI-MS), for determining 52 of most representative compounds of herbicides in water samples. The procedure used involved passing 0.5 l of surface water, 2 l of ground water and 4 l of drinking water samples, respectively, through a 0.5 g graphitized carbon black (GCB) extraction cartridge. Base-neutral and acid herbicides were differential eluted from GCB cartridge and follow analyzed by HPLC-ISI-MS apparatus. A conventional 4.6-mm-ID reversed-phase LC C18 column, operating with a mobile phase flow-rate of 1 ml/min, was used to chromatograph the analytes. A flow of 100 microl/min of the column effluent was diverted to the ISI source. The study demonstrates the sensitivity of the technique, with detection limit under 10 ng/l in drinking water samples. Performance data for the method such as recovery and precision are also reported.

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Chromatography, High Pressure LiquidEnvironmental MonitoringHerbicidesMass SpectrometryReproducibility of ResultsSensitivity and SpecificityWater Pollutants, ChemicalJournal ArticleResearch Support, Non-U.S. Gov't

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R Curini, A Gentili, S Marchese, A Marino, D Perret. 2000-04-07. Solid-phase extraction followed by high-performance liquid chromatography-ionspray interface-mass spectrometry for monitoring of herbicides in environmental water.. https://doi.org/10.1016/s0021-9673(00)00097-2

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