PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 10838007

Exploring the Visible Human using the VOXEL-MAN framework.

T Schiemann·J Freudenberg·B Pflesser·A Pommert·K Priesmeyer·M Riemer·R Schubert·U Tiede·K H Höhne
View original source ↗Export metadata ↓

Abstract

In principle the Visible Human data sets are an ideal basis for building electronic atlases. While it is easy to construct such atlases by just offering the possibility of browsing through the 2D slices, constructing realistic 3D models is a huge project. As one rather easy way to establish 3D use, we have registered the Visible Human data to the already existing 3D atlas VOXEL-MAN/brain. This procedure enables one to lookup anatomical detail in an atlas based on radiological images. Concerning the segmentation problem, which is the prerequisite for a real 3D atlas, we have developed an interactive classification method that delivers realistic perspective views of the Visible Human. As these volume based methods require high-end workstations, we finally have developed a multimedia program that runs on standard PCs and uses Quicktime VR movies.

Explore related subjects

Anatomy, Cross-SectionalComputer GraphicsFemaleHumansInformation Storage and RetrievalMaleJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

T Schiemann, J Freudenberg, B Pflesser, A Pommert, K Priesmeyer, M Riemer, R Schubert, U Tiede, K H Höhne. Exploring the Visible Human using the VOXEL-MAN framework.. https://doi.org/10.1016/s0895-6111(00)00013-6

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2002

Organ dose conversion coefficients for external photon irradiation of male and female voxel models.

New organ equivalent dose conversion coefficients are presented for whole body irradiation with monoenergetic photons of energies between 10 keV and 10 MeV for idealized geometries and seven adult male and female voxel models. The geometries are broad parallel photon beams in anterior-posterior, posterior-anterior, left- and right-lateral direction and a full 360 degree rotation around the body length axis. Dose differences between the different voxel models are below approximately 30% for some organs and geometries in the energy range between 60 and 200 keV, but they can be up to 100% or more in single cases, due to differences in stature and individual anatomical details. For low photon energies, the differences may amount to hundreds of per cent. Extensive comparisons of the dose conversion coefficients with respective values calculated using mathematical body models revealed various degrees of unrealistic positioning of single organs in the latter models. Examples are the kidneys, spleen and stomach that are located too superficially in the mathematical models. Over- or underestimations of several tens of per cent may, thus, occur for the mathematical models, compared to the voxel models considered. In contrast to previous assumptions, when the mathematical models have been used to establish reference organ dose conversion coefficients, it can be concluded that they do not properly represent a large population of individuals.

Anatomy, Cross-Sectional↗
PubMed2002

Optical projection tomography as a tool for 3D microscopy and gene expression studies.

Current techniques for three-dimensional (3D) optical microscopy (deconvolution, confocal microscopy, and optical coherence tomography) generate 3D data by "optically sectioning" the specimen. This places severe constraints on the maximum thickness of a specimen that can be imaged. We have developed a microscopy technique that uses optical projection tomography (OPT) to produce high-resolution 3D images of both fluorescent and nonfluorescent biological specimens with a thickness of up to 15 millimeters. OPT microscopy allows the rapid mapping of the tissue distribution of RNA and protein expression in intact embryos or organ systems and can therefore be instrumental in studies of developmental biology or gene function.

Anatomy, Cross-Sectional↗
PubMed2002

Transscleral optical coherence tomography: a new imaging method for the anterior segment of the eye.

OBJECTIVE: To present a new imaging method for the anterior segment of the eye. METHODS: Transscleral optical coherence tomographic images were generated in healthy volunteers using a slitlamp-adapted prototype equipped with a superluminescence diode with an infrared wavelength of 1310 nm. RESULTS: The optical coherence tomographic system used allowed penetration of human sclera in vivo and high-resolution, cross-sectional imaging of the anterior chamber angle and the ciliary body. CONCLUSION: The 1310-nm optical coherence tomographic image shows a significant potential as a noninvasive diagnostic tool for the anterior segment of the eye.

Anatomy, Cross-Sectional↗