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PubMed · 10850568

Coagulation problems in liver disease.

S I Rapaport
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Abstract

Three topics are addressed in this manuscript: (1) the causes of abnormal hemostasis in cirrhosis; (2) the evaluation of hemostasis in cirrhotic patients before invasive procedures or in the presence of bleeding; and (3) the assessment of the effect of recombinant activated factor VII (rFVIIa; NovoSeven, Novo Nordisk A/S, Bagsvaerd, Denmark) on hemostatic function in cirrhotic patients. Laboratory experiments are described that could enhance the understanding of the effect of rFVIIa on blood coagulation during hemostasis in cirrhotic patients.

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Blood CoagulationBlood Coagulation DisordersFactor VIIaFemaleHumansLiver DiseasesMaleRecombinant ProteinsThrombinJournal ArticleReview

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S I Rapaport. 2000. Coagulation problems in liver disease.. https://doi.org/10.1097/00001721-200004001-00014

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