Homer: a link between neural activity and glutamate receptor function.

B Xiao; J C Tu; P F Worley

doi:10.1016/s0959-4388(00)00087-8

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Homer: a link between neural activity and glutamate receptor function.

B Xiao·J C Tu·P F Worley

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Abstract

The proteins of the Homer family bind to proline-rich sequences in group I metabotropic glutamate receptors, inositol trisphosphate receptors, ryanodine receptors, and Shank family proteins. Homer proteins also self associate and function as adaptors to couple interacting proteins. Recent observations indicate a role for Homer complexes in signal transduction, synaptogenesis and receptor trafficking.

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Animals Carrier Proteins Homer Scaffolding Proteins Humans Neurons Neuropeptides Receptors, Glutamate Synaptic Transmission Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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B Xiao, J C Tu, P F Worley. 2000. Homer: a link between neural activity and glutamate receptor function.. https://doi.org/10.1016/s0959-4388(00)00087-8

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