Current tuberculosis vaccine development.

D B Young

doi:10.1086/313871

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PubMed · 10875794

Current tuberculosis vaccine development.

D B Young

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Abstract

Information derived from the complete genome sequence of Mycobacterium tuberculosis makes it possible to develop a range of new vaccine candidates. Strategies currently under investigation include construction of whole cell live attenuated mycobacterial vaccines, as well as the use of individual antigens delivered by a variety of subunit vaccination procedures. Fundamental questions associated with the rational design, preclinical testing, and future application of new tuberculosis vaccines are reviewed.

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Animals BCG Vaccine Bacterial Vaccines Drug Design Humans Mycobacterium tuberculosis Tuberculosis, Pulmonary Vaccines, Attenuated Vaccines, Synthetic Journal Article Review

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D B Young. 2000. Current tuberculosis vaccine development.. https://doi.org/10.1086/313871

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