Constructive antagonism in limb development.

A T Dudley; C J Tabin

doi:10.1016/s0959-437x(00)00101-5

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PubMed · 10889060

Constructive antagonism in limb development.

A T Dudley·C J Tabin

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Abstract

Several advances have been made in our understanding of the control of the growth and patterning of embryonic limbs. Development of the vertebrate limb is dependent on reciprocal interactions between the ectoderm and mesoderm that regulate the structure and function of the apical ectodermal ridge. One key component of this regulatory program appears to be the precise control of signaling by members of the bone morphogenetic protein family via multiple antagonistic interactions.

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Animals Body Patterning Bone Morphogenetic Proteins Extremities Fetal Proteins Formins Microfilament Proteins Nuclear Proteins Signal Transduction Transcription Factors Journal Article Research Support, Non-U.S. Gov't

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A T Dudley, C J Tabin. 2000. Constructive antagonism in limb development.. https://doi.org/10.1016/s0959-437x(00)00101-5

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