Synthesis of polypyrrolinones on solid support.

A B Smith; H Liu; H Okumura; D A Favor; R Hirschmann

doi:10.1021/ol005931u

PubMed · 10891225

Synthesis of polypyrrolinones on solid support.

A B Smith·H Liu·H Okumura·D A Favor·R Hirschmann

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Abstract

[reaction: see text] An efficient, three-step iterative synthesis of polypyrrolinones has been achieved on solid support, setting the stage for the construction of a wide variety of libraries based on the pyrrolinone scaffold. Central to the approach is an effective end-game sequence featuring pyrrolinone ring construction with traceless release from the solid support.

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Aldehydes Hydrolysis Indicators and Reagents Molecular Conformation Oxidation-Reduction Peptides Pyrrolidinones Journal Article Research Support, U.S. Gov't, P.H.S.

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A B Smith, H Liu, H Okumura, D A Favor, R Hirschmann. 2000-07-13. Synthesis of polypyrrolinones on solid support.. https://doi.org/10.1021/ol005931u

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Synthesis of polypyrrolinones on solid support.

Abstract

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Keep this discovery

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