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Immune responses in tuberculosis.

J L Flynn·J D Ernst
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Abstract

The initial interaction of Mycobacterium tuberculosis with phagocytes through Toll-like receptors can affect induction of the adaptive response by inflammatory cytokine production, as well as begin the process of bacterial containment by induction of antimycobacterial functions. Advances in T cell research in tuberculosis include identification of antigens recognized by CD8(+) T cells in infected hosts, elucidation of antimycobacterial mechanisms of T cells and the discovery of CD8(+) T cells that recognize antigens presented by a variety of non-classical molecules.

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AnimalsCD8-Positive T-LymphocytesDrosophila ProteinsHumansMembrane GlycoproteinsReceptors, Cell SurfaceToll-Like ReceptorsTuberculosisJournal ArticleReview

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J L Flynn, J D Ernst. 2000. Immune responses in tuberculosis.. https://doi.org/10.1016/s0952-7915(00)00116-3

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