Systemic and nontraditional markers of endothelial dysfunction.

A Gotlieb

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PubMed · 10906623

Systemic and nontraditional markers of endothelial dysfunction.

A Gotlieb

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Abstract

Endothelial cells control the balance between a number of opposing biological processes. Injury to these cells leads to a shift in this delicate balance; the resultant endothelial dysfunction ultimately leads to atherosclerotic disease. Specific markers of endothelial dysfunction can be used to detect and monitor the progression of atherosclerosis; they can also be used to study the pathogenesis of disease. Specific markers may be indicative of a particular stage in the pathogenesis of disease. By using a rigorous screening process, various markers of endothelial dysfunction can be identified. Common markers of endothelial dysfunction that are used in clinical studies are vascular cell adhesion molecule-1, intracellular adhesion molecule-1 and fibrinogen.

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Animals Arteries Arteriosclerosis Biomarkers Cell Adhesion Cell Adhesion Molecules Cell Communication Disease Progression Endothelium, Vascular Extracellular Matrix Proteins Humans Severity of Illness Index Journal Article Review

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A Gotlieb. 2000. Systemic and nontraditional markers of endothelial dysfunction.. https://pubmed.ncbi.nlm.nih.gov/10906623/

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