Platelet heparin-neutralizing factor (platelet factor 4).

E F Lüscher; R Käser-Glanzman

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PubMed · 1091019

Platelet heparin-neutralizing factor (platelet factor 4).

E F Lüscher·R Käser-Glanzman

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Abstract

The heparin-neutralizing platelet factor (PF4) is released from platelets under the influence of inducers of aggregation and nucleotide-release in the form of a high-molecular weight complex. The heparin-neutralizing activity is carried by a basic protein of molecular weight 29,700, four of which combine with a proteoglycan carrier, which in turn consists of 4 chondroitin sulfate A residues and a peptide moiety.

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Animals Blood Coagulation Factors Blood Platelets Chemical Phenomena Chemistry, Physical Heparin Antagonists Humans Molecular Weight Organoids Platelet Aggregation Protein Conformation Rats Journal Article Review

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E F Lüscher, R Käser-Glanzman. 1975-02-28. Platelet heparin-neutralizing factor (platelet factor 4).. https://pubmed.ncbi.nlm.nih.gov/1091019/

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