Replicating circular DNA molecules in yeast.

T D Petes; D H Williamson

doi:10.1016/0092-8674(75)90172-5

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Replicating circular DNA molecules in yeast.

T D Petes·D H Williamson

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Abstract

The yeast Saccharomyces cerevisiae contains a class of small circular DNA molecules, approximately 2 mum in contour length (Sinclair et al., 1967). In this report, it is shown that these molecules replicate as double-branched circles, similar to those observed during replication of the bacteriophage lambda and Escherichia coli chromosomes. A normal rate of replication of these DNA circles requires the function of a nuclear gene, cdc 8.

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Centrifugation, Density Gradient DNA Replication DNA, Circular Fluorescent Dyes Genes Microscopy, Electron Nucleic Acid Conformation Saccharomyces cerevisiae Journal Article

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T D Petes, D H Williamson. 1975. Replicating circular DNA molecules in yeast.. https://doi.org/10.1016/0092-8674(75)90172-5

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