PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 10916474

[Palindromic rheumatism].

J T Gran
View original source ↗Export metadata ↓

Abstract

BACKGROUND: Palindromic rheumatism is an inflammatory rheumatic disease characterised by recurrent attacks of arthritis confined to one or more peripheral joints. Each episode of arthritis rarely lasts more than 14 days, and subsides without leaving any residues. MATERIAL AND METHODS: Three patients with palindromic arthritis are presented, and the literature reviewed. RESULTS: The clinical and laboratory characteristics of the three patients were similar to those generally described for palindromic rheumatism. Two patients developed seropositive rheumatoid arthritis and one patient developed chronic seronegative polyarthritis. INTERPRETATION: Palindromic rheumatism may evolve into chronic polyarthritis.

Explore related subjects

ArthritisArthritis, RheumatoidDiagnosis, DifferentialFemaleHumansMiddle AgedRecurrenceCase ReportsEnglish AbstractJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

J T Gran. 2000-05-20. [Palindromic rheumatism].. https://pubmed.ncbi.nlm.nih.gov/10916474/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2007

Interleukin-18 genetics and inflammatory disease susceptibility.

IL18 was mapped to 11q22.2-22.3 in 1998. Owing to interleukin (IL)-18's important and novel role in immunomodulation, the gene itself has been subject to scrutiny, with the aim of discovering variants that may impact on disease susceptibility and/or progression. Despite being sequenced numerous times in different populations, no non-synonymous variants have been found. However, a number of polymorphisms within the proximal promoter have been verified that may interfere with transcription-factor-binding sites. Much of the subsequent association analyses have centred on these variants, but have yielded no consistent results, despite numerous different study populations being genotyped. IL18 has recently been resequenced in its entirety, enabling the tagging-single-nucleotide polymorphism (tSNP) methodology to be adopted. This approach has yielded interesting results, with genetic variation being shown to affect protein levels, and risk. This review aims to compile and reflect on the association data of interest published to date, with a focus on the diseases related to aberrant inflammatory control.

Arthritis↗