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PubMed · 10941565

Systemic chemotherapy.

V M Klimek·J D Wolchok·P B Chapman·A N Houghton·W J Hwu
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Abstract

The main use of systemic chemotherapy in metastatic melanoma remains palliative. Dacarbazine (dimethyl-1-triazeno imidazole-4-carboxamide [DTIC]) is the standard chemotherapy agent for advanced disease. The combination chemotherapy and biochemotherapy regimens have achieved higher response rates, but have not led to durable remission or improved survival. The field of systemic therapy remains in need of a more effective and less toxic treatment strategy.

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Antineoplastic AgentsAntineoplastic Agents, HormonalAntineoplastic Combined Chemotherapy ProtocolsDacarbazineHumansImmunotherapyMelanomaNeoadjuvant TherapyPalliative CareRemission InductionSkin NeoplasmsSurvival RateJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.Review

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V M Klimek, J D Wolchok, P B Chapman, A N Houghton, W J Hwu. 2000. Systemic chemotherapy.. https://pubmed.ncbi.nlm.nih.gov/10941565/

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