PubMed · 10973062
Conserved noncoding sequences are reliable guides to regulatory elements.
Abstract
A 'working draft' of the human genome sequence is now available. Comparisons with the sequences of mouse and other species will be a powerful approach to identifying functional segments of the noncoding regions, such as gene regulatory elements. However, the choice of a species for most effective comparison differs among various loci.
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R C Hardison. 2000. Conserved noncoding sequences are reliable guides to regulatory elements.. https://doi.org/10.1016/s0168-9525(00)02081-3
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