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PubMed · 10998617

Macromolecular structure determination by cryo-electron microscopy.

H R Saibil
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Abstract

Recent advances in transmission electron microscopy (EM) hardware, low-temperature methods and image-processing software have made cryo-EM an important complement to X-ray crystallography and NMR for macromolecular structure determination, particularly of large assemblies. This review provides a summary of the main advances and a survey of the capabilities of this approach.

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Cryoelectron MicroscopyCrystallography, X-RayFourier AnalysisImage Processing, Computer-AssistedModels, MolecularMolecular ConformationNuclear Magnetic Resonance, BiomolecularSoftwareJournal Article

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H R Saibil. 2000. Macromolecular structure determination by cryo-electron microscopy.. https://doi.org/10.1107/s0907444900010787

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