An answer to a complex problem: cloning the mouse t-complex responder.

M F Lyon

doi:10.1007/s003350010153

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An answer to a complex problem: cloning the mouse t-complex responder.

M F Lyon

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Abstract

The t-complex is maintained in wild mouse populations by its high transmission (up to 99%) from heterozygous males and provides an example of "meiotic drive". Its molecular basis has remained obscure despite long and intensive study. In a major advance, the t-complex responder gene, thought to be the key gene on which several distorters act, has now been cloned.

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Animals Chromosome Mapping Chromosomes Cloning, Molecular Forecasting Intracellular Signaling Peptides and Proteins Male Mice Microtubule-Associated Proteins Nuclear Proteins Ubiquitin-Protein Ligases t-Complex Genome Region Journal Article Review

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M F Lyon. 2000. An answer to a complex problem: cloning the mouse t-complex responder.. https://doi.org/10.1007/s003350010153

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