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Biocompatibility correlation of polymeric materials using human osteosarcoma cells.

K E Geckeler·R Wacker·W K Aicher
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Abstract

Metal implants are the preferred materials to generate articular prostheses, plates, or bone pegs in orthopedic surgery. Although titanium and titanium alloys show a relatively good biocompatibility, clinical experience revealed that coating of the metallic implant surface may increase the biocompatibility. In a search for optimum bone implant surfaces, we determined polarity and contact angle parameters of a variety of polymers and substances and correlated the findings in a biocompatibility assay using an in vitro bone cell model. We report that an optimum adherence of SAOS-2 cells to such surfaces and a good vitality for polymers are characterized by water-based contact angles of 80 degrees and 20 degrees for advancing and receding probes, respectively.

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Biocompatible MaterialsGlassHumansMitochondriaOsteosarcomaPolycarboxylate CementPolymethyl MethacrylatePolystyrenesPolyvinyl ChloridePolyvinylsProstheses and ImplantsTumor Cells, CulturedJournal Article

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K E Geckeler, R Wacker, W K Aicher. 2000. Biocompatibility correlation of polymeric materials using human osteosarcoma cells.. https://doi.org/10.1007/s001140050738

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