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A space-time adaptive method for simulating complex cardiac dynamics.

E M Cherry·H S Greenside·C S Henriquez
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Abstract

For plane-wave and many-spiral states of the experimentally based Luo-Rudy 1 model of heart tissue in large (8 cm square) domains, we show that a space-time-adaptive time-integration algorithm can achieve a factor of 5 reduction in computational effort and memory-but without a reduction in accuracy-when compared to an algorithm using a uniform space-time mesh at the finest resolution. Our results indicate that such an algorithm can be extended straightforwardly to simulate quantitatively three-dimensional electrical dynamics over the whole human heart.

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AlgorithmsArrhythmias, CardiacBiophysical PhenomenaBiophysicsComputer SimulationElectrophysiologyHeartHumansModels, CardiovascularComparative StudyJournal Article

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BibTeXRIS

E M Cherry, H S Greenside, C S Henriquez. 2000-02-07. A space-time adaptive method for simulating complex cardiac dynamics.. https://doi.org/10.1103/physrevlett.84.1343

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