Light sensitive chloramphenicol analogues.

P E Nielsen; V Leick; O Buchardt

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PubMed · 1103535

Light sensitive chloramphenicol analogues.

P E Nielsen·V Leick·O Buchardt

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Abstract

Some chloramphenicol analogues have been prepared in order to find reagents which could be used in a photoaffinity labelling study of the peptidayl transferase center of the E. coli ribosome. The compounds were tested for antibiotic activity in vitro in the "fragment reaction" assay, and for their ability to generate very reactive species upon irradiation.

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Chloramphenicol Depression, Chemical Escherichia coli Light Peptidyl Transferases Photochemistry Radiation Effects Ribosomes Ultraviolet Rays Journal Article

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P E Nielsen, V Leick, O Buchardt. 1975. Light sensitive chloramphenicol analogues.. https://pubmed.ncbi.nlm.nih.gov/1103535/

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