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PubMed · 1104733

A technique for intensifying BCG sensitivity.

S R Parmett·E Klein
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Abstract

Sensitization to BCG (Bacille Calmette-Guérin) appears to be more effective when it is carried out at the site of a delayed hypersensitivity challenge reaction to DNCB (1-chloro, 2,4-dinitrobenzene) than when it is carried out at unchallenged sites in non-sensitized animals. The effectiveness of BCG sensitization was determined by measurement of the intensity of the PPD (Purified Protein Derivative of tuberculin) 24-hour skin test. Possible mechanisms for this phenomenon and its implications for cancer immunotherapy are considered.

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AnimalsBCG VaccineDinitrochlorobenzeneGuinea PigsHypersensitivity, DelayedImmunity, CellularImmunotherapyMycobacterium bovisNeoplasmsNitrobenzenesTuberculin TestJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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S R Parmett, E Klein. 1975. A technique for intensifying BCG sensitivity.. https://pubmed.ncbi.nlm.nih.gov/1104733/

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