Axonal flip-flops and oscillators.

M D Baker

doi:10.1016/s0166-2236(00)01645-3

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Axonal flip-flops and oscillators.

M D Baker

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Abstract

The strange and unpleasant sensations (paraesthesiae) or asynchronous motor-unit activation (fasciculation) that result from a period of limb ischaemia are examples of ectopic discharge in peripheral nerves. Ectopic activity also results from demyelination and is associated with serious neurological conditions, such as multiple sclerosis. A build-up of extracellular K(+) in the internode and persistent Na(+) currents are now implicated in generating the different forms of activity arising in normal and demyelinated axons.

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Animals Axons Electrophysiology Extremities Humans Ischemia Models, Neurological Oscillometry Paresthesia Journal Article Research Support, Non-U.S. Gov't Review

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M D Baker. 2000. Axonal flip-flops and oscillators.. https://doi.org/10.1016/s0166-2236(00)01645-3

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