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PubMed · 11091925

Lung cancer. Diagnostic tools.

M Goldberg·M Unger
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Abstract

Early diagnosis of lung cancer represents the best method for improving survival rates. The diagnostic aids available have improved exponentially on old and new techniques over the past 20 years. The greatest impact has been in computed tomography and positron emission tomography scanning imaging techniques. In the future, these techniques will improve, and others such as monoclonal antibody scans and antisense imaging techniques will certainly further enhance the physician's ability to diagnose earlier, and thereby, treat earlier.

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Biopsy, NeedleBronchoalveolar LavageBronchoscopyClinical Trials as TopicFluorescenceFluorodeoxyglucose F18Genes, Tumor SuppressorHumansLungLung NeoplasmsMagnetic Resonance ImagingMediastinoscopyMulticenter Studies as TopicOligonucleotides, AntisenseRadiography, ThoracicRadiopharmaceuticalsRetrospective StudiesSputumThoracic Surgery, Video-AssistedThoracoscopyTomography, Emission-ComputedTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedJournal ArticleReview

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M Goldberg, M Unger. 2000. Lung cancer. Diagnostic tools.. https://pubmed.ncbi.nlm.nih.gov/11091925/

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Targeting difficult accessible breast lesions: MRI-guided needle localization using a freehand technique in a 3.0 T closed bore magnet.

PURPOSE: To report the accuracy of magnetic resonance imaging (MRI)-guided needle localization for diagnosis of MRI detected suspicious breast lesions located in difficult accessible regions of the breast, using the freehand method in a 3.0 T closed bore magnet. MATERIALS AND METHODS: In five patients with five MRI-only breast lesions underwent MRI-guided needle localization for histopathologic evaluation of the lesions. All interventional procedures were performed in a 3.0 T MRI system with the patient in prone position and by using a dedicated phased array breast coil. MRI-guided needle localizations were performed by using a freehand technique. In our study, the high-resolution scan allowed preprocedural localization of all lesions without use of contrast enhancement. In all cases contrast-enhanced MRI was performed after insertion of the wire to confirm the tip of the wire in direct contact with the enhancing lesion. RESULTS: Needle localizations were performed in five patients. Histopathologic evaluation of tissue after surgery excision biopsy revealed one lymph node, three invasive ductal carcinoma and one ductal carcinoma in situ. Lesion size varied from 6 to 30 mm. Mean duration time was 25 min. No complications occurred during the intervention method. In the patient with the benign lesion control MRI of the breast after 6 months confirmed lesion removal. CONCLUSIONS: MRI-guided needle localization by using a freehand technique in a 3.0 T closed bore magnet is a safe and accurate method for diagnosis of difficult accessible breast lesions only visible on MRI.

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