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PubMed · 11114537

Membrane targeting: what a difference a G makes.

P J Cullen·P Chardin
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Abstract

Pleckstrin homology domains are modular domains that direct membrane targeting of their host proteins by binding to polyphosphoinositides; recent results have increased our appreciation of how some of these domains actually bind 3-phosphoinositides, and along the way thrown up some unexpected observations.

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Adaptor Proteins, Signal TransducingAgammaglobulinaemia Tyrosine KinaseBlood ProteinsCell MembraneFatty AcidsGTPase-Activating ProteinsGlycineLipoproteinsPhosphatidylinositol PhosphatesPhosphoproteinsProtein Structure, SecondaryProtein Structure, TertiaryProtein-Tyrosine KinasesProteinsReceptors, Cytoplasmic and NuclearSignal TransductionJournal ArticleResearch Support, Non-U.S. Gov't

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P J Cullen, P Chardin. 2000-11-30. Membrane targeting: what a difference a G makes.. https://doi.org/10.1016/s0960-9822(00)00818-6

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