[Optimality of enzymatic physiological systems].

K V Tiurin; M A Khanin

PubMed · 11149314

[Optimality of enzymatic physiological systems].

Abstract

An optimality criterion is proposed for physiological systems based on limited proteolysis. The proposed criterion is applied to the prourokinase-activated fibrinolytic system, for which the existence of optimal (according to this criterion) substrate concentrations is demonstrated. It is also shown that the optimal substrate concentrations depend on the values of kinetic constants.

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Animals Enzyme Activation Enzymes Fibrinolysis Kinetics Models, Biological Plasminogen Activators Protein Precursors Proteins Urokinase-Type Plasminogen Activator English Abstract Journal Article

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K V Tiurin, M A Khanin. [Optimality of enzymatic physiological systems].. https://pubmed.ncbi.nlm.nih.gov/11149314/

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