Clinically relevant rat model for testing BOLD functional MR imaging techniques by using single-shot echo-planar imaging at 1.5 T.

D W Morton; K R Maravilla; J R Meno; H R Winn

doi:10.1148/radiology.218.2.r01fe30598

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Clinically relevant rat model for testing BOLD functional MR imaging techniques by using single-shot echo-planar imaging at 1.5 T.

D W Morton·K R Maravilla·J R Meno·H R Winn

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Abstract

By using a 1.5-T whole-body magnetic resonance (MR) imager, a high-spatial-resolution single-shot echo-planar technique was developed to perform blood oxygen level dependent functional MR imaging of rat sensory cortex during forepaw stimulation. This technique produced cubic 1-mm(3) voxels. Signal-to-noise ratio was 140-160 (43-44 dB). Optimal effective echo time was 50 msec. This system should prove useful for developing new functional MR imaging techniques with rapid adaptation to human use.

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Animals Brain Echo-Planar Imaging Humans Magnetic Resonance Imaging Male Oxygen Rats Rats, Sprague-Dawley Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

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D W Morton, K R Maravilla, J R Meno, H R Winn. 2001. Clinically relevant rat model for testing BOLD functional MR imaging techniques by using single-shot echo-planar imaging at 1.5 T.. https://doi.org/10.1148/radiology.218.2.r01fe30598

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