Calcium signalling--an overview.

M D Bootman; T J Collins; C M Peppiatt; L S Prothero; L MacKenzie; P De Smet; M Travers; S C Tovey; J T Seo; M J Berridge; F Ciccolini; P Lipp

doi:10.1006/scdb.2000.0211

PubMed · 11162741

Calcium signalling--an overview.

M D Bootman·T J Collins·C M Peppiatt·L S Prothero·L MacKenzie·P De Smet·M Travers·S C Tovey·J T Seo·M J Berridge·F Ciccolini·P Lipp

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Abstract

Calcium (Ca2+) is an almost universal intracellular messenger, controlling a diverse range of cellular processes, such as gene transcription, muscle contraction and cell proliferation. The ability of a simple ion such as Ca2+ to play a pivotal role in cell biology results from the facility that cells have to shape Ca2+ signals in the dimensions of space, time and amplitude. To generate the variety of observed Ca2+ signals, different cell types employ components selected from a Ca2+ signalling 'toolkit', which comprizes an array of signalling, homeostatic and sensory mechanisms. By mixing and matching components from the toolkit, cells can obtain Ca2+ signals that suit their physiology.

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Animals Calcium Calcium Channels Calcium Signaling Homeostasis Humans Journal Article Review

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BibTeX RIS

M D Bootman, T J Collins, C M Peppiatt, L S Prothero, L MacKenzie, P De Smet, M Travers, S C Tovey, J T Seo, M J Berridge, F Ciccolini, P Lipp. 2001. Calcium signalling--an overview.. https://doi.org/10.1006/scdb.2000.0211

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