PubMed Health⌕ Search

PubMed · 11163617

Closed-loop and open-loop accommodative vergence eye movements.

Abstract

We examined accommodative vergence eye movements under conditions in which feedback about retinal-image slip was and was not present (i.e. closed-loop and open-loop conditions). We found that (a) in both conditions the two eyes started to move at the same time; (b) in the open-loop condition, vergence continued in both eyes; and (c) in the closed-loop condition, vergence continued in the occluded eye only, and the magnitude and velocity exceeded that of the occluded eye in the open-loop condition by a factor of two.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

S Saida, H Ono, A P Mapp. 2001. Closed-loop and open-loop accommodative vergence eye movements.. https://doi.org/10.1016/s0042-6989(00)00233-9

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Ocular symptoms in children treated with human-mouse chimeric anti-GD2 mAb ch14.18 for neuroblastoma.

Unusual ocular symptoms observed during intravenous treatment with anti-disialoganglioside antibody (Ab) in children suffering from neuroblastoma were analyzed and the results reported. Within the framework of the German Collaborative Neuroblastoma Study NB97, 85 children with high-risk neuroblastoma received anti-GD2 monoclonal antibody ch14.18 intravenously. Side effects were regularly reported to the study center. Ocular symptoms were recorded in clinical detail, duration and development over time. Symptoms of a parasympathetic deficit corresponding to internal ophthalmoplegia, i.e. mydriasis and accommodation deficit, were found in 10 patients. They were uni- or bilateral, began after the termination of Ab infusion and improved or disappeared in all surviving children. They did not reappear or worsen upon repeated Ab infusions. The pathophysiology of these disorders remains poorly understood. It is concluded that during systemic treatment with the anti-GD2 antibody ch14.18, reversible symptoms of parasympathetic denervation of the eye may occur which, however, do not warrant termination of this treatment.

Accommodation, Ocular↗

[Children and adolescents with Down syndrome. Continuous ophthalmological monitoring crucial!].

Children with Down's syndrome are at increased risk of ocular manifestations, which is confirmed by a study in Uppsala, Sweden. Sixty percent of the children were wearing glasses and/or had other ocular problems. However, lapses were found in follow-up and referral to the eye clinic. Good visual function is an important prerequisite for optimal quality of life of children and adults with Down's syndrome. Since this group does not always spontaneously get in touch with the health care system including ophthalmologists, the infant must be referred by the pediatrician immediately after birth. The number of individuals with Down's syndrome in Sweden is large (3,500-5,000), and an ophthalmological follow-up program, as presented in this paper, is of key importance.

Accommodation, Ocular↗