Bordetella pertussis, molecular pathogenesis under multiple aspects.

C Locht; R Antoine; F Jacob-Dubuisson

doi:10.1016/s1369-5274(00)00169-7

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Bordetella pertussis, molecular pathogenesis under multiple aspects.

C Locht·R Antoine·F Jacob-Dubuisson

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Abstract

Recent studies, including those based on genomics, have demonstrated that besides toxins and adhesins, Bordetella pertussis uses many additional virulence determinants. Most of them are part of the BvgAS regulon, although some, in particular iron-uptake systems, are independent of BvgAS. They are regulated by iron, although in one case, the production of a siderophore receptor could be linked to the BvgAS regulon.

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Adhesins, Bacterial Antigens, Bacterial Bacterial Proteins Bacterial Toxins Bordetella pertussis Hemagglutinins Humans Iron Lipopolysaccharides Signal Transduction Transcription Factors Virulence Virulence Factors, Bordetella Journal Article Research Support, Non-U.S. Gov't Review

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C Locht, R Antoine, F Jacob-Dubuisson. 2001. Bordetella pertussis, molecular pathogenesis under multiple aspects.. https://doi.org/10.1016/s1369-5274(00)00169-7

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