Post-transplant biliary problems.

J W Ostroff

Home/Archive/PubMed

PubMed · 11175980

Post-transplant biliary problems.

J W Ostroff

View original source ↗Export metadata ↓

Abstract

Biliary problems after a liver transplantation constitute the most frequent source of morbidity. Early recognition and nonoperative therapy have impacted short-term survival. Endoscopic therapy is the cornerstone in the initial treatment of all post-transplant biliary complications. A multidisciplinary approach involving endoscopic, percutaneous, and surgical therapies are often complementary in the management of these complex patients.

Explore related subjects

Anastomosis, Surgical Arterial Occlusive Diseases Bile Ducts Biliary Tract Diseases Catheterization Constriction, Pathologic Hepatic Artery Humans Liver Transplantation Living Donors Journal Article Review

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

J W Ostroff. 2001. Post-transplant biliary problems.. https://pubmed.ncbi.nlm.nih.gov/11175980/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2003

[Prophylactic routine anastomotic drainage in elective colorectal surgery: systematic review and metanalysis].

OBJECTIVE: To analyse the results of the comparison of the use or not of routine prophylactic drainage of anastomoses after elective colorectal surgery. The following hypothesis will be tested: the use of routine prophylactic drainage of anastomoses after elective colorectal surgery is unjustified.

Anastomosis, Surgical↗

PubMed2003

Persistent anastomosis between proper hepatic and replaced right hepatic artery: implications in liver transplantation.

Explore the source record for details and available documents.

Anastomosis, Surgical↗

PubMed2003

The cholecystocolic bypass with jejunal interposition graft for bile acid depletion in bile and portal blood in guinea pigs.

Ileal bypass and cholecystostomy are used in children with selected cholestatic diseases to lower the bile acid (BA) levels in bile and blood and improve outcome. The efficacy of a cholecystocolic bypass in achieving the same goals was investigated in guinea pigs. In the study group (n=7), a cholecystocolic bypass was performed using a jejunal graft interposed between the gallbladder and the cecum. In the control group (n=5), a cholecystojejunal bypass was performed with a similar graft implanted in the proximal jejunum. Total BA concentration was measured in bile and portal blood at surgery (D0) and 30 days later (D30) by pooling the concentrations of 7 individual BA. D30/D0 BA ratios were compared. All animals developed normally without clinical symptoms. A 76% reduction in the bile T-BA levels was observed in both groups (p<0.05). A 80% decrease of T-BA levels was observed in portal vein in study group (p<0.05), suggesting that ileal bile flow and BA ileal reabsorption were highly impaired. No change in portal vein BA levels was observed in control group. Cholecystocolic bypass led to a significant loss of bile acids in guinea pigs and might be considered for bile diversion in pediatric patients with selected cholestatic diseases.

Anastomosis, Surgical↗